Grade 2-3 plasmacytosis is considered diagnostic. Please see below for examples supported by written guidance from a member of our expert panel.
This tool has been funded and produced by Recordati. All images have been provided by an international
panel of expert pathologists.
The concept, functionality and expert guidance found within this tool has
also
been developed with the support of expert pathologists.
EXPERT GUIDANCE
Plasmacytosis: Grade 3
This H&E section shows a prominent increase of plasma cells in the paracortical area. These cells should be polytypic (expressing a mixture of kappa (brown) and lambda (red) light chains) and show no expression of IgG4.
Abbreviations
H&E, hematoxylin and eosin; IgG4, immunoglobulin G4.
This tool has been funded and produced by Recordati. All images have been provided by an international panel of expert pathologists. The concept, functionality and expert guidance found within this tool has also been developed with the support of expert pathologists.
EXPERT GUIDANCE
Plasmacytosis: Grade 1
This H&E section of the paracortical area of a cervical lymph node shows a slight increase in plasma cells.
Abbreviations
H&E, hematoxylin and eosin.
This tool has been funded and produced by Recordati. All images have been provided by an international panel of expert pathologists. The concept, functionality and expert guidance found within this tool has also been developed with the support of expert pathologists.
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